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Synthese mittlerer und großer Ringe, XXVII. Chromatographische Enantiomerentrennung von 3,6‐Heptanophthalid – ein Beitrag zur Frage der absoluten Konfiguration von [ n ]Paracyclophancarbonsäuren
Author(s) -
Tochtermann Werner,
Olsson Gese,
Mannschreck Albrecht,
Stühler Georgine,
Snatzke Günther
Publication year - 1990
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19901230638
Subject(s) - chemistry , enantiomer , stereochemistry , absolute configuration , chromatographic separation , chromatography , high performance liquid chromatography
Synthesis of Medium and Large Rings, XXVII 1 . ‐ Chromatographic Separation of the Enantiomeric 3.6‐Heptanophthalides. ‐ A Contribution to the Problem of the Absolute Configuration of [nJ Paracyclophanecarboxylic Acids The partial chromatographic separation of the racemic title compound 1 (ee = 40%) was achieved on triacetylcellulose with ethanol using a recycling technique. Comparison of the CD spectra of (+) 22 365 ‐ 1 with (+) 22 365 ‐ 2 leads to the absolute configuration ( P ) for both compounds. This assignment is of interest in view of earlier configurational assignments for [ n ]paracyclophanecarboxylic acids.