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Optical Resolution of [2,2]Paracyclophanes by High‐Performance Liquid Chromatography on Tris(3,5‐dimethylphenylcarbamates) of Celllulos and Amylose
Author(s) -
Hopf Henning,
Gruhn Walter,
Barrett David G.,
Gerdes Anton,
Hibner Jörg,
Hucker Joachim,
Okamoto Yoshio,
Kaida Yuriko
Publication year - 1990
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19901230432
Subject(s) - chemistry , enantiomer , amylose , high performance liquid chromatography , tris , cyclophane , chromatography , resolution (logic) , cellulose , organic chemistry , molecule , biochemistry , artificial intelligence , starch , computer science
Optical resolution of 22 [2,2]paracyclophane derivatives was examined by high‐performance liquid chromatography (HPLC) using tris(3,5‐dimethylphenylcarbamates) of cellulose and amylose as chiral stationary phases. Most compounds were completely separated into enantiomers at least on one of the stationary phases. The preparation of hte new cyclophane derivatives 10, 11, 12, 14, 16 , and 19 as wel as a new procedure for the synthesis of 4‐fluoro‐[2,2]paracyclophane ( 3 ) are described.