Premium
Reaktionen von Pentacarbonyl(trifluormethylisocyanid)chrom mit Nucleophilen
Author(s) -
Lentz Dieter,
Marschall Robert
Publication year - 1990
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19901230417
Subject(s) - chemistry , nucleophile , isocyanide , carbene , trifluoromethyl , medicinal chemistry , chromium , moiety , reagent , ylide , stereochemistry , organic chemistry , catalysis , alkyl
Reactions of Pentacarbonyl(trifluoromethyl isocyanide)chromium with Nucleophiles Pentacarbonyl(trifluoromethyl isocyanide)chromium ( 1 ) reacts with nucleophilic reagents like secondary amines ( 2a‐d ), 1,2‐dimethylhydrazine ( 2e ), or methanol ( 2f ). The first nucleophilic attack occurs at the isocyanide carbon atom. The formed Fischer‐type carbene complexes readily eliminate HF under the reaction conditions forming a difluoromethanimine moiety, which is further attacked by the nucleophile. The isolated products are carbene complexes of the type (CO) 5 Cr[C(NR 2 ]N=C(NR 2 )F] ( 3a‐c ), (CO) 5 Cr[C(NR 2 )N=C(NR 2 ) 2 ]( 3d ), (CO) 5 Cr[CN(CH 3 )N(CH) 3 C{N(CH 3 )H}=N] ( 3e ), and (CO) 5 Cr(C(OCH 3 )N=C(OCH 3 ) 2 ] ( 3f ). The structure of 3c has been determined by an X‐ray crystal structure analysis.