Synthese von Sieben‐ und Achtring‐anellierten Pyridinen durch “inverse” intramolekulare Diels‐Alder‐Reaktion mit Trifluormethyl‐substituierten 1,2,4‐Triazinen | Zendy

John Rainer | Zendy; Seitz Gunther | Zendy

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Synthese von Sieben‐ und Achtring‐anellierten Pyridinen durch “inverse” intramolekulare Diels‐Alder‐Reaktion mit Trifluormethyl‐substituierten 1,2,4‐Triazinen

Author(s) -

John Rainer,

Seitz Gunther

Publication year - 1990

Publication title -

chemische berichte

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.667

H-Index - 136

eISSN - 1099-0682

pISSN - 0009-2940

DOI - 10.1002/cber.19901230125

Subject(s) - chemistry , bicyclic molecule , cycloaddition , intramolecular force , trifluoromethyl , intramolecular reaction , ring (chemistry) , medicinal chemistry , stereochemistry , alkyne , diels–alder reaction , catalysis , organic chemistry , alkyl

Synthesis of Seven‐ and Eight‐Membered Ring‐Annulated Pyridines by “Inverse” Intramolecular Diels‐Alder Reaction with Trifluoromethyl‐Substituted 1,2,4‐Triazines Intramolecular [4 + 2] cycloaddition reactions with inverse electron demand of trifluoromethyl‐substituted 1,2,4‐triazines carrying 7‐ or 8‐membered o‐alkyne side‐chain dienophiles ( 3,8,12 ) lead to the synthesis of bicyclic pyridines with annulated heterocyclic seven‐ ( 5, 9, 13‐15 ) or eight‐membered rings ( 19, 22, 23, 26 ).

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