Premium
Reaktionen mit Aziridinen, 41 Hoch regioselektive (anomale) Ringöffnung von 1‐Benzoyl‐2,2‐dimethylaziridin durch einfache Nitril‐Anionen
Author(s) -
Assithianakis Petros,
Stamm Helmut
Publication year - 1987
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19871200528
Subject(s) - chemistry , aziridine , pyrrolidine , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry
The anions 3a–e of the acetonitriles 2a–e cleave the aziridine ring of 1‐benzoyl‐2,2‐dimethylaziridine ( 1 ) at the tertiary Catom (abnormal opening) and provide in this way good yields of the 4‐(benzoylamino)‐3,3‐dimethylbutyronitriles 5a–e and of the 2‐(benzoylimino)pyrrolidine 7a , respectively. Positional isomers could not be detected.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom