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Reaktionen mit Aziridinen, 41 Hoch regioselektive (anomale) Ringöffnung von 1‐Benzoyl‐2,2‐dimethylaziridin durch einfache Nitril‐Anionen
Author(s) -
Assithianakis Petros,
Stamm Helmut
Publication year - 1987
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19871200528
Subject(s) - chemistry , aziridine , pyrrolidine , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry
The anions 3a–e of the acetonitriles 2a–e cleave the aziridine ring of 1‐benzoyl‐2,2‐dimethylaziridine ( 1 ) at the tertiary Catom (abnormal opening) and provide in this way good yields of the 4‐(benzoylamino)‐3,3‐dimethylbutyronitriles 5a–e and of the 2‐(benzoylimino)pyrrolidine 7a , respectively. Positional isomers could not be detected.