Premium
Fluorierung ungesättigter Aldehyde mit Schwefeltetrafluorid
Author(s) -
Haas Alois,
Plümer Rita,
Schiller Achim
Publication year - 1985
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19851180733
Subject(s) - chemistry , dehydrohalogenation , trifluoromethyl , cyclohexene , cyclohexane , medicinal chemistry , aldehyde , organic chemistry , catalysis , alkyl
Fluorination of Unsaturated Aldehydes with Sulfur Tetrafluoride Fluorination of unsaturated aldehydes 1 with SF 4 in the presence of KF at 20°C leads to the corresponding difluoromethyl‐substituted compounds 2 in various yields. Dehydrohalogenation of 1‐bromo‐1‐(difluoromethyl)‐ ( 2b ) or 1‐bromo‐1‐(trifluoromethyl)cyclohexane ( 5b ) gives 1‐(difluoromethyl)‐ ( 2a ) or 1‐(trifluoromethyl)‐1‐cyclohexene ( 5c ), respectively.