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Heterocyclic β‐Enamino Esters, 34. New Types of Spiro Compounds by Addition and Cyclization Reactions of 3‐(2‐Imidazolidinylidene)‐ and 3‐(Tetrahydro‐2(1 H )‐pyrimidinylidene)dihydro‐2(3 H ‐furanones with Methyl Acrylate and Dimethyl Acetylenedicarboxylate
Author(s) -
Huang ZhiTang,
Wamhoff Heinrich
Publication year - 1984
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19841170521
Subject(s) - chemistry , dimethyl acetylenedicarboxylate , acrylate , benzene , sequence (biology) , methyl acrylate , medicinal chemistry , addition reaction , organic chemistry , stereochemistry , cycloaddition , catalysis , polymer , monomer , copolymer , biochemistry
The 2(3 H ‐furanones 1a – e react with methyl acrylate in benzene or dioxane solution to afford the spiro compounds 2a – e in an addition and cyclocondensation reaction sequence. With dimethyl acetylenedicarboxylate 1a, b give merely the addition products 3a, b , while 1c – e yields the spiro compounds 4a – c in a related addition‐cyclocondensation step.