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Notizen. 5‐ und 6‐Ring‐Reduktone aus 2‐Diazo‐1,3,dicarbonyl‐verbindungen. Eine schonende Alternative zur klassischen “Verkochungsmethode”
Author(s) -
Schank Kurt,
Blattner Rudolf
Publication year - 1981
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19811140533
Subject(s) - chemistry , diazo , sodium iodide , sodium hypochlorite , formic acid , ring (chemistry) , medicinal chemistry , hydrolysis , organic chemistry , hypochlorite , acetic acid , iodide
Five‐ and Six‐Membered Ring Reductones from 2‐Diazo‐1,3‐dicarbonyl Compounds. A Smoothful Alternative of the Classic Thermal Dediazotation 2‐Acyloxy‐2‐chloro‐1,3‐dicarbonyl compounds 2 , easily obtained from 2‐diazo‐1,3‐dicarbonyl compounds 1 , and tert ‐butyl hypochlorite in formic or acetic acid at room temperature or below, are immediately reduced to the corresponding reductone esters 3 , by sodium iodide/disodium pentaoxodisulfate. (Concomitant) Hydrolysis of the reductone esters yields the desired reductones 4 .