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Doppel‐Ionophor mit Dihydrotetraaza[14]annulen‐ und Kronenether‐Funktion
Author(s) -
Kruse Rolf,
Breitmaier Eberhard
Publication year - 1981
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19811140246
Subject(s) - chemistry , ionophore , annulene , stereochemistry , ligand (biochemistry) , medicinal chemistry , cobalt , chelation , diamine , inorganic chemistry , polymer chemistry , calcium , receptor , organic chemistry , biochemistry
Double‐Ionophore with Dihydrotetraaza[14]annulene‐ and Crownether‐Function Benzo[15]crown‐5 ( 1 ) was converted in four steps into the 4‐amino‐5‐nitro‐derivative 5 , which, after reduction to the diamine 6 , cyclocondenses with 3‐ethoxy‐2‐isopropylacrolein. The resulting trimacrocyclic ligand 7 chelates nickel(II) and cobalt(II) ions and, additionally, potassium and sodium ions, thus being a double ionophore.