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Synthese und Reaktionen von neuen 3‐Chlor‐ N ‐[chlor(dialkyl‐amino)methylen]benzo[ b ]thiophen‐2‐carboxamiden
Author(s) -
Ried Walter,
Oremek Gerhard,
Guryn Roman
Publication year - 1980
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19801130724
Subject(s) - chemistry , methylene , thiophene , medicinal chemistry , nucleophile , thio , stereochemistry , organic chemistry , catalysis
Synthesis and Reactions of New 3‐Chloro‐ N ‐[chloro(dialkylamino)methylene]benzo[ b ]thio‐phene‐2‐carboxamides The substituted 3‐chlorobenzo[ b ]thiophene‐2‐carbonyl chlorides 2) 2a‐h react with cyanamides 1a – e to form the 3‐chloro‐ N ‐[chloro(dialkylamino)methylene]benzo[ b ]thiophene‐2‐carboxamides 3a – m . By exchanging the Cl‐atom of the chloroformamidine group in 3e with a O‐, S‐ or N‐nucleophile we produced the new compounds 6 – 11 .