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Chromatographische Racemattrennungen, IX. Chlortalidon‐, Chlortalidon‐methylether‐ und Oxazepam‐Enantiomere
Author(s) -
Blaschke Gottfried,
Markgraf Hildegunde
Publication year - 1980
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19801130538
Subject(s) - oxazepam , chemistry , enantiomer , optically active , ether , amide , chromatography , stereochemistry , organic chemistry , biochemistry , benzodiazepine , receptor
Chromatographie Resolutions of Racemates, IX. Chlorotalidone‐, Chlorotalidone Methyl Ether‐, and Oxazepam Enantiomers The racemic drugs chlorotalidone ( 2a ) and oxazepam ( 3 ) are completely, chlorotalidone methyl ether ( 2b ) partially resolved by chromatography on the optically active amide 1. 2a and 3 racemize under the influence of acids and bases.
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