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2,2‐Disubstituierte 1,3‐Dithiane aus β‐Dicarbonylverbindungen
Author(s) -
Stahl Ingfried,
Manske Rainer,
Gosselck Jürgen
Publication year - 1980
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19801130238
Subject(s) - chemistry , yield (engineering) , hydrolysis , dithiane , medicinal chemistry , combinatorial chemistry , organic chemistry , materials science , metallurgy
2,2‐Disubstituted 1,3‐Dithianes from β‐Dicarbonyl Compounds 1,3‐Dicarbonyl compounds 2 can be condensed with 1,3‐propanedithiol ( 1 ) to yield 2,2‐disubstituted 1,3‐dithianes 3 which are remarkably stable in contrast to analogous open‐chain thioacetals 6 . Compounds with alkoxycarbonyl functions are easily hydrolysed to the corresponding carboxylic acids 11 which by further esterification with alkanols 12 yield estermodified 1,3‐dithianes 3 . All new compounds are characterized by 13 C NMR spectroscopy.