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Eine verbesserte Methode zur Darstellung von 1,3,3‐Triethyl‐2‐methylenindolin
Author(s) -
Gamon Norbert,
Reichardt Christian
Publication year - 1980
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19801130138
Subject(s) - chemistry , yield (engineering) , tetrafluoroborate , medicinal chemistry , alkylation , ethanol , salt (chemistry) , organic chemistry , ionic liquid , catalysis , materials science , metallurgy
An Improved Method for the Synthesis of 1,3,3‐Triethyl‐2‐methyleneindoline 1,3,3‐Triethyl‐2‐methyleneindoline ( 8 ) has been synthesized in 40% yield by alkylation of 2‐methylindole with iodoethane in ethanol at 100 – 110°C/50 bar using an improved separation procedure. The 1 H‐ and 13 C‐NMR spectra of 8 and its tetrafluoroborate salt are examined.