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Ribosidierung von 7 H ‐Pyrrolo[2,3‐d]pyrimidin‐4(3 H )‐on an N‐3
Author(s) -
Lüpke Uwe,
Seela Frank
Publication year - 1979
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19791121021
Subject(s) - chemistry , stereochemistry , residue (chemistry) , glycosidic bond , nucleoside , medicinal chemistry , organic chemistry , enzyme
Ribosidation of 7 H ‐Pyrrolo[2,3‐d] pyrimidin‐4(3 H )‐one at N‐3 The ribosidation of 7 H ‐pyrrolo[2,3‐ d ] pyrimidin‐4(3 H )‐one ( 2a ) With 2,3,5,‐tri‐ O ‐acetyl‐ribofuranosyl bormide (Wittenburg conditions) yields the N‐3 nucleoside ( 3a ). The glycosidic residue is directed towards N‐7 or 4‐O by spacious substituents at C‐2.