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Phasentransferkatalysierte Wittig‐Reaktionen ohne Basenzusatz
Author(s) -
Koßmehl Gerhard,
Nuck Rolf
Publication year - 1979
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19791120642
Subject(s) - wittig reaction , chemistry , phosphonium , halide , catalysis , ylide , organic chemistry , medicinal chemistry
Basefree Wittig Reactions with Phase Transfer Catalyts Ketones like trifluoroacetyl compounds — giving the haloform reaction in basic solutions — are able to react with mono or bis phosphonium fluorides without bases via Wittig reactions with very good yields. The phosphonium fluorides are prepared very easily from other phosphonium halides under phase transfer catalysis of crown ethers. The ratio of the stereoisomeric alkenes in the product and the spectra of the trans ‐ respectively trans‐trans alkenes are given.