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Indoleninoxide, VI: Katalyse einer Isomerisierung durch Ethentetracarbonitril und Oxirantetracarbonitril
Author(s) -
Dopp Dietrich,
NourelDin Ahmed Mokhtar
Publication year - 1978
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19781111221
Subject(s) - isomerization , chemistry , catalysis , yield (engineering) , medicinal chemistry , molar ratio , organic chemistry , materials science , metallurgy
Indolenine Oxides, VI: Catalysis of an Isomerization by Ethenetetracarbonitrile and Oxiranetetracarbonitrile Ethenetetracarbonitrile ( 2 ) or oxiranetetracarbonitrile ( 7 ), when applied in quantities of 0.1 mol per mol of 1 , are effective in isomerizing the 3H ‐indole 1‐oxide 1 into the thermodynamically more stable lactam 4 in high yield. If either 2, 7 , or tetracyanoquinodimethan ( 8 ) are applied to 1 in 1:1 molar ratios, the yields of isomerization product 4 tend to drop. — A trivial acid catalysis brought about by contamination by acidic impurities may be excluded for the isomerization of 1 by 2 .