Synthese der Cycloamide der  xylo ‐3′‐Amino‐3′‐desoxyadenosin‐5′‐phosphorsäure und −5′‐thionophosphorsäure, zweier neuer cAMP‐Analoga | Zendy

Morr Michael | Zendy; Mengel Rudolf | Zendy

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Synthese der Cycloamide der xylo ‐3′‐Amino‐3′‐desoxyadenosin‐5′‐phosphorsäure und −5′‐thionophosphorsäure, zweier neuer cAMP‐Analoga

Author(s) -

Morr Michael,

Mengel Rudolf

Publication year - 1977

Publication title -

chemische berichte

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.667

H-Index - 136

eISSN - 1099-0682

pISSN - 0009-2940

DOI - 10.1002/cber.19771101227

Subject(s) - chemistry , deoxyadenosine , chloride , phosphoric acid , phosphoryl chloride , yield (engineering) , stereochemistry , medicinal chemistry , adenosine , organic chemistry , biochemistry , materials science , metallurgy

Synthesis of the Cycloamides of xylo ‐3′‐Amino‐3′‐deoxyadenosine −5′‐phosphoric Acid and −5′‐thionophosphoric Acid, two New cAMP Analogues xylo ‐3′‐Amino‐3′‐deoxyadenosine ( 1 ) reacts with phosphoryl chloride or with thiophosphoryl chloride to yield the adenosine‐3′,5′‐cyclophosphates 3a or 3b , respectively, in high yields.

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