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Neolignans and Sesquiterpenoid from Piper yunnanense
Author(s) -
Chen YuXi,
You YunXia,
Rao Li,
Liu Yu,
He Qian,
Xu YouKai,
Lin Bin,
Zhang ChuanRui
Publication year - 2021
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.202100458
Subject(s) - dibenzofuran , chemistry , stereochemistry , piper , circular dichroism , antimicrobial , piperaceae , biphenyl , linkage (software) , phenanthrenes , botany , biochemistry , organic chemistry , biology , phenanthrene , gene
Two biphenyl‐type neolignans with a rare dibenzofuran skeleton, including a new one piyunneolignan A ( 1 ) and a known one piperneolignan D ( 2 ), together with a new sesquiterpenoid piyunin A ( 3 ), were isolated from the leaves and twigs of Piper yunnanense . Their structures were established on the basis of comprehensive spectroscopic data analysis and electronic circular dichroism (ECD) calculation. Piyunneolignan A ( 1 ) featured a rare C‐2−C‐2′/C‐3−O−C‐3′ linkage. Compounds 1 – 3 were evaluated for their antimicrobial and cytotoxic activities against a panel of bacteria, fungi, and human cancer cell lines, respectively.