Commiphoranes K−O, New Terpenoids from Resina Commiphora and Their Anti‐Inflammatory Activities

Commiphorane K ( 1 ), a new dinorditerpenoid, commiphoranes L−N ( 2 – 4 ), three new germacrane‐type sesquiterpenoids, and commiphorane O ( 5 ), one new guaiane‐type sesquiterpenoid, were isolated from Resina Commiphora . Their structures were characterized by spectroscopic and computational methods. In particular, the structure of 4 was confirmed by X‐ray crystallography. Compounds 2 – 5 were evaluated for their anti‐inflammatory activities. The result shows that compound 2 suppresses lipopolysaccharide (LPS)‐stimulated production of TNF‐ α in RAW264.7 cells in a dose‐dependent manner.