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Front Cover: Julichrome Monomers from Marine Gastropod Mollusk‐Associated Streptomyces and Stereochemical Revision of Julichromes Q 3 ⋅ 5 and Q 3 ⋅ 3 (C&B 4/2020)
Author(s) -
Dong Yuliang,
Ding Wenjuan,
Sun Changli,
Ji Xiaoqi,
Ling Chunyao,
Zhou Zhenbin,
Chen Zhiyun,
Chen Xuehong,
Ju Jianhua
Publication year - 2020
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.202000202
Subject(s) - micrococcus luteus , front cover , bacillus subtilis , staphylococcus aureus , bacteria , chemistry , streptomyces , antibacterial activity , micrococcus , marine bacteriophage , bioassay , isolation (microbiology) , stereochemistry , microbiology and biotechnology , biology , ecology , cover (algebra) , mechanical engineering , engineering , genetics
Front Cover . Bacteria living symbiotically within marine invertebrates often confer the ability to generate bioactive natural products to fight off potential predators or to compete for living space. A microbial symbiont, Batillaria zonalis associated Streptomyces sampsonii SCSIO 054, was found displaying antibacterial activity against Gram‐positive bacteria. Bioassay‐guided isolation of the crude extract resulted in the isolation of two new julichrome monomers, namely julichrome Q 11 and Q 12 , along with nine known julichrome analogues. This is the first report of julichromes isolated from a marine source. Significant antibacterial activities of these compounds against Micrococcus luteus , Bacillus subtilis , and an array of methicillin‐resistant Staphylococcus aureus , S. aureus and S. simulans AKA1 were observed, as reported by Ju et al . in their full paper at 10.1002/cbdv.202000057.