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Front Cover: Noncovalent Spin‐Labeling of DNA and RNA Triplexes (C&B 2/2020)
Author(s) -
Kamble Nilesh,
Wolfrum Manpreet,
Halbritter Thomas,
Sigurdsson Snorri T.,
Richert Clemens
Publication year - 2020
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.202000030
Subject(s) - chemistry , dna , guanine , covalent bond , base pair , rna , non covalent interactions , stereochemistry , nucleobase , dissociation (chemistry) , molecule , nucleotide , hydrogen bond , biochemistry , gene , organic chemistry
Front Cover . Designed DNA and RNA triplexes may be spin‐labeled using the guanine derivative shown in the upper right‐hand corner of the cover graphic. The labeling does not require a covalent bond and is based on Watson‐Crick plus Hoogsteen base pairing of the guanine base and unpaired pyrimidines of the triplex. The resulting complexes have dissociation constants in the micromolar range, as reported by Kamble and Wolfrum et al . in their full paper at 10.1002/cbdv.201900676.