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Secondary Metabolites from Marine Micromonospora : Chemistry and Bioactivities
Author(s) -
Qi Sisi,
Gui Min,
Li Huanhuan,
Yu Chunbo,
Li Hongji,
Zeng Zheling,
Sun Peng
Publication year - 2020
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.202000024
Subject(s) - micromonospora , chemistry , antiparasitic , terpene , biochemistry , biology , bacteria , streptomyces , medicine , genetics , pathology
Marine Micromonospora was revealed to be a rather untapped and a rich source of chemically diverse and unique bioactive natural products. This review is aimed to make a comprehensive survey of secondary metabolites that were derived from marine Micromonospora including chemical diversity and biological activities. A total of 116 compounds from 41 marine Micromonospora species have been reported, covering the literatures from 1997 to 2019. These compounds contain several structural classes such as polyketides (PKS), nonribosomal peptides (NRPS), PKS‐NRPS hybrids, terpenes and others, and they present cytotoxic, antibacterial, antiparasitic, chemopreventive or antioxidant activities.