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Cover Picture: Antimycotic Activity Potentiation of Allium sativum Extract and Silver Nanoparticles against Trichophyton rubrum (C&B 4/2019)
Author(s) -
RoblesMartínez Marissa,
González Juan Fernando Cárdenas,
PérezVázquez Francisco Javier,
MontejanoCarrizales Juan Martín,
Pérez Elías,
PatiñoHerrera Rosalba
Publication year - 2019
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201900149
Subject(s) - trichophyton rubrum , chemistry , allium sativum , silver nanoparticle , antifungal , sativum , minimum inhibitory concentration , nuclear chemistry , food science , botany , in vitro , microbiology and biotechnology , nanoparticle , biochemistry , nanotechnology , biology , materials science
Cover Picture . Silver nanoparticles (AgNPs) with a diameter of 26 ± 7 nm were synthesized and their activity was examined against Trichophyton rubrum ( T. rubrum ), a concentration of 0.08 mg ml –1 inhibited 94% of growth. Also, Allium sativum (garlic) extract was obtained ( As Ext), and its MIC was 0.04 mg ml –1 . To increase antifungal capacity of those systems, As Ext was decorated with AgNPs, obtaining As Ext‐AgNPs. Using an As Ext concentration of 0.04 mg ml –1 in independent experiments with concentrations from 0.01 to 0.08 mg ml –1 of AgNPs it was possible to inhibit T. rubrum at all AgNPs concentrations; it proves a synergetic effect between AgNPs and As Ext. Even if 1% of the minimum inhibitory concentration of As Ext (0.0004 mg ml –1 ) is used, it was possible to inhibit T. rubrum at all concentrations of AgNPs, demonstrating the successful antimycotic activity potentiation when combining As Ext and AgNPs, as reported by Robles‐Martínez and Patiño‐Herrera et al . in their full paper at 10.1002/cbdv.201800525.