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Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin
Author(s) -
Huang XiaoJun,
Li Ping,
Yin ZhiQi,
Lu JinJian,
Lin LiGen,
Wang Ying,
Ye WenCai,
Zhang QingWen
Publication year - 2019
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201900137
Subject(s) - pogostemon , chemistry , epimer , glycosidic bond , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , organic chemistry , traditional medicine , enzyme , medicine
A pair of new glycosidic epimers, cablinosides A ( 1a ) and B ( 1b ) were isolated from the leaves of Pogostemon cablin . The structures with absolute configurations of 1a and 1b were elucidated by extensive NMR investigation, and quantum chemical CD calculations. The epimer mixture 1 showed moderate α ‐glucosidase inhibitory activity and no significant cytotoxic activity against HepG2 cells.