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Chromane Enantiomers from the Flower Buds of Tussilago farfara L. and Assignments of Their Absolute Configurations
Author(s) -
Sun Jia,
Yu JinHai,
Zhang JunSheng,
Song XiuQing,
Bao Jie,
Zhang Hua
Publication year - 2019
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201800581
Subject(s) - chemistry , antimicrobial , enantiomer , absolute (philosophy) , absolute configuration , stereochemistry , organic chemistry , philosophy , epistemology
Fourteen chromane derivatives of seven pairs of enantiomers ( 1 – 14 ) have been obtained from the ethanolic extract of the flower buds of Tussilago farfara L. Their structures with absolute configurations have been elucidated by detailed spectroscopic analyses, chemical methods, and particularly comparison of experimental ECD spectra with theoretically computed ones. Biological evaluations revealed that they did not show cytoprotective, antimicrobial, and α ‐ glucosidase inhibitory activities.