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Cover Picture: Biological Evaluation of a New Lignan from the Roots of Rice ( Oryza sativa ) (C&B 11/2018)
Author(s) -
Lee Tae Kyoung,
Lee Dahae,
Yu Jae Sik,
Jo Mun Seok,
Baek Su Cheol,
Shin MyoungSook,
Ko YoonJoo,
Kang Ki Sung,
Kim Ki Hyun
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201800537
Subject(s) - lignan , oryza sativa , cytotoxicity , chemistry , phytochemical , enterolactone , oryza , botany , traditional medicine , biochemistry , biology , stereochemistry , in vitro , endocrinology , phytoestrogens , estrogen , medicine , gene
Cover Picture . LC/MS‐based phytochemical analysis of an EtOH extract of the roots of rice ( Oryza sativa ; Gramineae) resulted in the isolation of a new lignan, oryzativol C ( 1 ). Compound 1 showed mild cytotoxicity toward the breast cancer cell line (MDA‐MB‐231). Furthermore, compound 1 stimulated insulin secretion in INS‐1 pancreatic β‐cells without inducing cytotoxicity. These results indicate that compound 1 is an active ingredient of O. sativa that offers health benefits including inhibition of breast cancer cell proliferation and hyperglycemia control as reported by Lee et al . in their full paper at https://doi.org/10.1002/cbdv.201800333.
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