Three New Monoterpenoid Indole Alkaloids from  Ervatamia pandacaqui | Zendy

Zhang Jian | Zendy; Ao YunLin | Zendy; Yao Nan | Zendy; Bai WenXin | Zendy; Fan ChunLin | Zendy; Ye WenCai | Zendy; Zhang XiaoQi | Zendy

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Three New Monoterpenoid Indole Alkaloids from Ervatamia pandacaqui

Author(s) -

Zhang Jian,

Ao YunLin,

Yao Nan,

Bai WenXin,

Fan ChunLin,

Ye WenCai,

Zhang XiaoQi

Publication year - 2018

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201800268

Subject(s) - chemistry , indole test , cytotoxicity , hydrolysis , stereochemistry , sugar , apocynaceae , organic chemistry , biochemistry , botany , in vitro , biology

Three new monoterpenoid indole alkaloids, ervapandine A ( 1 ), (3 R )‐hydroxyibogaine ( 3 ), 12‐hydroxyakuammicine N (4)‐oxide ( 6 ), along with four known ones, were isolated from the twigs and leaves of Ervatamia pandacaqui . The structures of the new alkaloids were elucidated by spectroscopic methods and sugar hydrolysis experiment. All of the compounds were evaluated for their cytotoxicity against three human cell lines. Compound 7 showed moderate cytotoxic activity.

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