Premium
Design, Synthesis, and Antifungal Activities of Novel 1,2,4‐Triazole Schiff Base Derivatives
Author(s) -
Jin Ruyi,
Liu Jingli,
Zhang Guanghui,
Li Jiajia,
Zhang Shuan,
Guo Hui
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201800263
Subject(s) - phytophthora capsici , fusarium , pythium , antifungal , chemistry , fusarium solani , schiff base , triazole , alternaria , alternaria solani , stereochemistry , microbiology and biotechnology , botany , biology , fungicide , organic chemistry , food science , pepper
With the aim to find new compounds with high antifungal activity, 21 4‐amino‐5‐substituted‐1,2,4‐triazole Schiff bases ( 2a – 2g , 3a – 3g , and 4a – 4g ) were designed and synthesized. Their antifungal activities against Pythium solani , Gibberlla nicotiancola , Fusarium oxysporium f. sp. niveum , Gibberlla saubinetii , Alternaria iycopersici , Phytophthora capsici , Physalospora piricola , Cercospora arachidicola hori , and Fusarium oxysporium f. sp. cucumber were tested, parts of the compounds exhibited excellent antifungal activity. This research provides useful information for further study of antifungal agents.