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Chemical Constituents of the Seed Cake of Camellia oleifera and Their Antioxidant and Antimelanogenic Activities
Author(s) -
Zhu WanFang,
Wang CiLi,
Ye Feng,
Sun HaoPeng,
Ma CongYu,
Liu WenYuan,
Feng Feng,
Abe Masahiko,
Akihisa Toshihiro,
Zhang Jie
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201800137
Subject(s) - camellia oleifera , chemistry , antioxidant , tyrosinase , camellia sinensis , food science , traditional medicine , in vitro , pomace , botany , biochemistry , enzyme , biology , medicine
There is a growing interest in the exploitation of agricultural byproducts. This study explored the potential beneficial health effects from the main biowaste, tea seed pomace of Camellia oleifera Abel (Theaceae), produced when tea seed is processed. Eighteen compounds were isolated from the 70% Et OH extract of the seed cake of C . oleifera . Their structures were determined by ESI ‐ MS , 1 H‐ and 13 C‐ NMR together with literature data. All fractions and compounds were evaluated for the antioxidant and melanogenesis inhibitory activities. As the result, Ac OE t fraction has the best in vitro antioxidant and antimelanogenesis activities, compounds 7 – 12 and 15 showed remarkable antioxidant activity, compounds 4 , 6 , 8 , and 15 – 17 exhibited superior inhibitory activities against melanogenesis. Furthermore, tyrosinase inhibitory activity assay suggested that compound 8 could suppress melanogenesis by inhibiting the expression of tyrosinase.