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Five New Alkaloids from the Roots of Sophora flavescens
Author(s) -
Zhang ShengYuan,
Li Wen,
Nie Hua,
Liao Mei,
Qiu Bo,
Yang YaLi,
Chen YanFen
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700577
Subject(s) - sophora flavescens , quinolizidine , chemistry , sparteine , cytisine , sophora , stereochemistry , staphylococcus aureus , alkaloid , escherichia coli , traditional medicine , chromatography , biochemistry , bacteria , biology , traditional chinese medicine , receptor , medicine , matrine , genetics , nicotinic agonist , pathology , gene , alternative medicine
Five new quinolizidine alkaloids, including three sparteine‐type alkaloids ( 1 – 3 ) and two cytisine‐type alkaloids ( 4 and 5 ), along with four known ones, were isolated from the roots of Sophora flavescens . Their structures were determined by extensive spectroscopic techniques including IR , UV , NMR , and HR ‐ ESI ‐ MS . All the compounds were evaluated for their antibacterial activities against Staphylococcus aureus and Escherichia coli .
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