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New Metabolites Produced by Cylindrocarpon sp. SY ‐39 from a Driftwood
Author(s) -
Suzuki Takuma,
Yoshida Seiya,
Koseki Takuya,
Aboshi Takako,
Murayama Tetsuya,
Supratman Unang,
Shiono Yoshihito
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700493
Subject(s) - chemistry , staphylococcus aureus , antimicrobial , stereochemistry , microbiology and biotechnology , bacteria , organic chemistry , biology , genetics
Four novel compounds, cylindropyrone A ( 1 ), 10′‐hydroxyilicicolinic acid D ( 3 ), cylindrolactones A ( 4 ) and B ( 5 ), together with known dihydroinfectopyrone ( 2 ) were isolated from the culture of Cylindrocarpon sp. SY ‐39 from a driftwood. Their structures were elucidated using 1D‐ and 2D‐ NMR spectroscopy. Compound 3 showed antimicrobial activity against Staphylococcus aureus with MIC value of 5.0 μg/mL.