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Protostane‐Type Triterpenoids from Alisma orientale
Author(s) -
Li HongMei,
Chen XueJiao,
Luo Dan,
Fan Min,
Zhang ZhiJun,
Peng LiYan,
Wu XingDe,
Li RongTao,
Ji Xu,
Zhao QinShi
Publication year - 2017
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700452
Subject(s) - rhizome , triterpenoid , chemistry , terpene , triterpene , traditional medicine , stereochemistry , medicine , alternative medicine , pathology
Twenty‐eight protostane triterpenoids, including a new degraded one ( 1 ), nine new ones ( 2 – 10 ), and two new natural ones ( 11 and 12 ), have been isolated from the dried rhizomes of Alisma orientale . Alisol R ( 1 ) was the first 20,21,22,23,24,25,26,27‐octanorprotostane triterpenoid. The absolute configurations of 25‐methoxyalisol F ( 2 ) and 16 β ‐hydroperoxyalisol B 23‐acetate ( 3 ) were determined by X‐ray diffraction analysis. In addition, alismaketone‐B 23‐acetate ( 28 ) showed potent vasorelaxant activity on endothelium‐intact thoracic aorta rings precontracted with KCl.
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