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Four New Acylated Iridoid Glycosides from the Aerial Part of Veronicastrum sibiricum and Their Antioxidant Response Element‐Inducing Activity
Author(s) -
Kim Myeong Il,
Kim Chul Young
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700447
Subject(s) - iridoid , chemistry , glycoside , antioxidant , stereochemistry , traditional medicine , biochemistry , medicine
Four new ( 1 – 4 ) and one known ( 5 ) acylated iridoid glycosides were isolated from the aerial parts of Veronicastrum sibiricum (L.) Pennell . The chemical structures of the isolated compounds were determined to be 3″,4″‐dicinnamoyl‐6‐ O ‐rhamnopyranosyl‐10‐ O ‐bergaptol‐5,7‐bisdeoxycynanchoside ( 1 ), 3″,4″‐dicinnamoyl‐6‐ O‐ rhamnopyranosylpaulownioside ( 2 ), 2″,4″‐dicinnamoyl‐6‐ O ‐rhamnopyranosylcatalpol ( 3 ), 3″,4″‐dicinnamoyl‐6‐ O ‐rhamnopyranosylaucubin ( 4 ), and 3″,4″‐dicinnamoyl‐6‐ O ‐rhamnopyranosylcatalpol ( 5 ) using spectroscopic techniques. Among these compounds, compound 5 increased antioxidant response element (ARE) luciferase activity.