Premium
Bioactive Pimarane‐Type Diterpenes from Marine Organisms
Author(s) -
Wang Xiaoli,
Yu Haobing,
Zhang Yixin,
Lu Xiaoling,
Wang Bin,
Liu Xiaoyu
Publication year - 2018
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700276
Subject(s) - diterpene , antimicrobial , chemistry , computational biology , natural (archaeology) , biology , stereochemistry , organic chemistry , paleontology
Marine organisms represent an abundant sources of bioactive natural products with unique chemical structure. Pimarane diterpenes are a structurally diverse family of natural products with various biological activities and pharmacological properties. A prolific source of new marine‐derived pimarane diterpenes have attracted considerable interest because of their unique structural diversity and varied biological activities, including antimicrobial, antitumor, and antiproliferative activities. This review provides a comprehensive overview of the structures, names, bioactivities, and references of 80 marine‐derived pimarane‐type natural products for the first time.