New Prenylated  ortho ‐Dihydroxycoumarins from the Fruits of  Ficus nipponica | Zendy

Akihara Yui | Zendy; Ohta Emi | Zendy; Nehira Tatsuo | Zendy; Ômura Hisashi | Zendy; Ohta Shinji | Zendy

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New Prenylated ortho ‐Dihydroxycoumarins from the Fruits of Ficus nipponica

Author(s) -

Akihara Yui,

Ohta Emi,

Nehira Tatsuo,

Ômura Hisashi,

Ohta Shinji

Publication year - 2017

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201700196

Subject(s) - ficus , prenylation , chemistry , bacillus subtilis , coumarin , antibacterial activity , botany , stereochemistry , bark (sound) , traditional medicine , bacteria , biology , organic chemistry , enzyme , medicine , genetics , ecology

Two new prenylated ortho ‐dihydroxycoumarins, designated fipsomin ( 1 ) and fipsotwin ( 2 ), were isolated from the fruits of Ficus nipponica together with a known prenylated coumarin, apigravin ( 3 ). Their structures were established by spectroscopic data and X‐ray crystallographic analysis. Compound 1 exhibited antibacterial activity against Bacillus subtilis with an MIC value of 61 μ m , while 2 and 3 showed very weak activity.

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