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Four New Nanaomycins Produced by Streptomyces hebeiensis Derived from Lichen
Author(s) -
Liu Chengbin,
Jiang Yi,
Lei Hui,
Chen Xiu,
Ma Qingjuan,
Han Li,
Huang Xueshi
Publication year - 2017
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201700057
Subject(s) - antimicrobial , lichen , chemistry , streptomyces , fungus , fermentation , microorganism , bacteria , microbiology and biotechnology , stereochemistry , food science , botany , organic chemistry , biology , genetics
Four new nanaomycins ( 1 – 4 ), together with two known compounds, nanaomycin α A ( 5 ) and nanaomycin β A ( 6 ) were isolated from a fermentation broth of Streptomyces hebeiensis derived from lichen. The structures of the new nanaomycins 1 – 4 were established using comprehensive NMR spectroscopic data analysis as well as UV , IR , and MS data. The antimicrobial activities of 1 – 6 were evaluated against Gram ‐positive bacteria and fungus. Compounds 5 and 6 showed antimicrobial activities against the test microorganisms, while 1 – 4 were inactive at 100 μg/ml.
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