A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant  Pterocephalus nestorianus   Nábělek | Zendy

Abdullah Fuad O. | Zendy; Hussain Faiq H. S. | Zendy; Clericuzio Marco | Zendy; Porta Alessio | Zendy; Vidari Giovanni | Zendy

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A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Author(s) -

Abdullah Fuad O.,

Hussain Faiq H. S.,

Clericuzio Marco,

Porta Alessio,

Vidari Giovanni

Publication year - 2017

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201600281

Subject(s) - dimer , chemistry , iridoid , stereochemistry , kaempferol , traditional medicine , biochemistry , flavonoid , organic chemistry , glycoside , medicine , antioxidant

Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside ( 1 ), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus , which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D‐ and 2D‐ NMR spectroscopic data. Kaempferol 3‐ O ‐[3,6‐di‐ O ‐( E )‐ p ‐coumaroyl]‐ β ‐ d ‐glucopyranoside ( 7 ) showed a remarkable antiproliferative activity against several human tumor cell lines.

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