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Essential Oils Composition and Antimicrobial Activity of Six Conifers Harvested in Lebanon
Author(s) -
Fahed Layal,
Khoury Madona,
Stien Didier,
Ouaini Naïm,
Eparvier Véronique,
El Beyrouthy Marc
Publication year - 2017
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201600235
Subject(s) - chemistry , antimicrobial , composition (language) , chemical composition , essential oil , food science , traditional medicine , botany , organic chemistry , biology , medicine , philosophy , linguistics
The chemical composition and antimicrobial activity of the essential oils ( EO s) of six conifers harvested in Lebanon, Abies cilicica , Cupressus sempervirens , Juniperus excelsa , Juniperus oxycedrus , Cedrus libani and Cupressus macrocarpa gold crest, were investigated. The EO s were obtained by hydrodistillation using a Clevenger ‐type apparatus and characterized by GC and GC / MS analyses. A principal components analysis based on Pearson correlation between essential oils chemical analyses was also conducted. The minimum inhibitory concentrations ( MIC s) of these essentials oils were determined against a range of bacteria and fungi responsible for cutaneous infections in human, using the broth microdilution technique. The EO s showed the most interesting bioactivity on the dermatophytes species ( MIC values 32 – 64 μg/ml). Each of the major compounds of C . macrocarpa as well as an artificial reconstructed EO were tested on Trichophyton rubrum showing a contribution of the minor components to the overall activity.