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Chemical Diversity and Antimicrobial Activity of Salvia multicaulis Vahl Essential Oils
Author(s) -
Fahed Layal,
Stien Didier,
Ouaini Naïm,
Eparvier Véronique,
El Beyrouthy Marc
Publication year - 2016
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201500332
Subject(s) - nerolidol , antimicrobial , chemotype , essential oil , traditional medicine , chemistry , broth microdilution , minimum inhibitory concentration , staphylococcus aureus , botany , biology , microbiology and biotechnology , food science , bacteria , linalool , medicine , genetics
The chemical compositions and antimicrobial activities of the essential oils ( EO s) of aerial parts of Salvia multicaulis Vahl , collected during the same week from two different Lebanese regions, were investigated. The EO s were obtained by hydrodistillation using a Clevenger ‐type apparatus and characterized by GC and GC / MS analyses. The minimum inhibitory concentrations of these EO s were determined against one Gram ‐negative and two Gram ‐positive bacteria, one yeast, and five dermatophytes using the broth microdilution technique. One EO was notably active against Staphylococcus aureus , methicillin‐resistant S. aureus , and all of the Trichophyton species tested. Nerolidol was found to be the major compound in the active oil; nerolidol was also absent from the inactive oil. This study demonstrated that nerolidol shows antimicrobial activity and therefore significantly contributes to the antimicrobial potential of the oil. The chemical diversity of worldwide S. multicaulis EO s was analyzed, revealing that the EO s of this study belong to two different chemotypes found in the literature. The nerolidol chemotype appears to be restricted to Lebanon, and it can be used as antimicrobial agent against external bacterial and fungal infections.