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Polygonifoliol, a New Tirucallane Triterpene from the Latex of the Seaside Sandmat Euphorbia polygonifolia
Author(s) -
Giner JoséLuis,
Schroeder Timothy N.
Publication year - 2015
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201400426
Subject(s) - triterpene , euphorbia , chemistry , terpene , euphorbiaceae , genus , chemotaxonomy , stereochemistry , alcohol , botany , organic chemistry , biology , taxonomy (biology) , alternative medicine , pathology , medicine
The genus Euphorbia contains over 2000 species which exhibit a considerable diversity of di‐ and triterpenes in their latex. The North American species Euphorbia polygonifolia is a low growing plant of Atlantic and Great Lake beaches. The composition of its free and esterified triterpene alcohols was determined by HPLC and 1 H‐NMR analyses. An unreported triterpene alcohol was found as 2.6% and 10.3% of the free and esterified fractions, respectively. The structure of the new triterpene alcohol was determined using HMBC, and its configurational assignment was secured by acid‐catalyzed isomerization to isotirucallol. The new compound, polygonifoliol, was shown to be Δ 12 ‐isotirucallol.