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Three New Isomeric Indole Alkaloids from Nauclea officinalis
Author(s) -
Wang HaiYang,
Wang RuXia,
Zhao YanXia,
Liu Ke,
Wang FengLing,
Sun JingYong
Publication year - 2015
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201400289
Subject(s) - chemistry , indole test , stereochemistry , organic chemistry
Three new isomeric monoterpene indole alkaloids, naucleofficines I–III ( 1 – 3 , resp.) were isolated from the stems (with bark) of Nauclea officinalis. Their structures were elucidated on the basis of spectroscopic methods and single‐crystal diffraction analyses. The cytotoxic activities of 1 – 3 against human colon cancer, human gastric cancer, and human hepatoma cells were also investigated.