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New Isoprenylated Phenolic Compounds from Morus laevigata
Author(s) -
Wang Meng,
Yu BangWei,
Yu MeiHua,
Gao LiXin,
Li JingYa,
Wang HeYao,
Li Jia,
Hou AiJun
Publication year - 2015
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201400210
Subject(s) - chemistry , taxifolin , in vitro , stereochemistry , traditional medicine , biochemistry , flavonoid , antioxidant , medicine
Abstract Two new isoprenylated flavonoids, laevigasins A and B ( 1 and 2 , resp.), and one new isoprenylated 2‐arylbenzofuran, leavigasin C ( 3 ), together with eight known compounds, 4 – 11 , were isolated from the twigs of Morus laevigata . Their structures were elucidated by spectroscopic methods. Laevigasin A ( 1 ) showed significant inhibitory effect on α ‐glucosidase in vitro. Notabilisin E ( 5 ), taxifolin ( 10 ), and hultenin ( 11 ) inhibited PTP1B phosphatase activity in vitro.