New Isoprenylated Phenolic Compounds from  Morus laevigata | Zendy

Wang Meng | Zendy; Yu BangWei | Zendy; Yu MeiHua | Zendy; Gao LiXin | Zendy; Li JingYa | Zendy; Wang HeYao | Zendy; Li Jia | Zendy; Hou AiJun | Zendy

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New Isoprenylated Phenolic Compounds from Morus laevigata

Author(s) -

Wang Meng,

Yu BangWei,

Yu MeiHua,

Gao LiXin,

Li JingYa,

Wang HeYao,

Li Jia,

Hou AiJun

Publication year - 2015

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201400210

Subject(s) - chemistry , taxifolin , in vitro , stereochemistry , traditional medicine , biochemistry , flavonoid , antioxidant , medicine

Two new isoprenylated flavonoids, laevigasins A and B ( 1 and 2 , resp.), and one new isoprenylated 2‐arylbenzofuran, leavigasin C ( 3 ), together with eight known compounds, 4 – 11 , were isolated from the twigs of Morus laevigata . Their structures were elucidated by spectroscopic methods. Laevigasin A ( 1 ) showed significant inhibitory effect on α ‐glucosidase in vitro. Notabilisin E ( 5 ), taxifolin ( 10 ), and hultenin ( 11 ) inhibited PTP1B phosphatase activity in vitro.

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