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Seven New Sesquiterpenoids from the Fruits of Schisandra sphenanthera
Author(s) -
Tsai YaoChing,
Cheng YuanBin,
Lo IWen,
Cheng HoHsi,
Lin ChingJie,
Hwang TsongLong,
Kuo YuhChi,
Liou ShorongShii,
Huang YiZsau,
Kuo YaoHaur,
Shen YaChing
Publication year - 2014
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201300259
Subject(s) - chemistry , traditional medicine , schisandra , fractionation , tetralin , schisandra chinensis , stereochemistry , chromatography , organic chemistry , medicine , alternative medicine , pathology , traditional chinese medicine , catalysis
Fractionation of the EtOH extract from the fruits of Schisandra sphenanthera resulted in the isolation of seven new sesquiterpenoids, 1 – 7 , in addition to the known metabolites 8 – 23 . Among them, schiscupatetralin A ( 1 ) possesses an unprecedented structure with a CC bond between cuparenol and tetralin. The isolated new compounds were evaluated for their anti‐HSV‐1 and anti‐inflammatory activities. The results revealed that compound 4 exhibited anti‐HSV‐1 activity, while compound 6 showed a significant anti‐inflammatory activity.