Seven New Sesquiterpenoids from the Fruits of  Schisandra sphenanthera | Zendy

Tsai YaoChing | Zendy; Cheng YuanBin | Zendy; Lo IWen | Zendy; Cheng HoHsi | Zendy; Lin ChingJie | Zendy; Hwang TsongLong | Zendy; Kuo YuhChi | Zendy; Liou ShorongShii | Zendy; Huang YiZsau | Zendy; Kuo YaoHaur | Zendy; Shen YaChing | Zendy

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Seven New Sesquiterpenoids from the Fruits of Schisandra sphenanthera

Author(s) -

Tsai YaoChing,

Cheng YuanBin,

Lo IWen,

Cheng HoHsi,

Lin ChingJie,

Hwang TsongLong,

Kuo YuhChi,

Liou ShorongShii,

Huang YiZsau,

Kuo YaoHaur,

Shen YaChing

Publication year - 2014

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201300259

Subject(s) - chemistry , traditional medicine , schisandra , fractionation , tetralin , schisandra chinensis , stereochemistry , chromatography , organic chemistry , medicine , alternative medicine , pathology , traditional chinese medicine , catalysis

Fractionation of the EtOH extract from the fruits of Schisandra sphenanthera resulted in the isolation of seven new sesquiterpenoids, 1 – 7 , in addition to the known metabolites 8 – 23 . Among them, schiscupatetralin A ( 1 ) possesses an unprecedented structure with a CC bond between cuparenol and tetralin. The isolated new compounds were evaluated for their anti‐HSV‐1 and anti‐inflammatory activities. The results revealed that compound 4 exhibited anti‐HSV‐1 activity, while compound 6 showed a significant anti‐inflammatory activity.

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