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Antifungal Bromophenols from Marine Red Alga Symphyocladia latiuscula
Author(s) -
Xu Xiuli,
Yin Liyuan,
Gao Junhai,
Gao Lijie,
Song Fuhang
Publication year - 2014
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201300239
Subject(s) - antifungal , chemistry , botany , microbiology and biotechnology , biology
Three new highly brominated polyphenols, 1 – 3 , together with one known bromophenol, 4 , were isolated from the EtOH extract of a marine red alga Symphyocladia latiuscula collected from the coast of Qingdao, P. R. China. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data. Compounds 3 and 4 showed activities against the Candida albicans with the MIC values of 25 and 12.5 μg/ml, respectively.