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Cytotoxic Polyphenols from a Sponge‐Associated Fungus Aspergillus versicolor Hmp‐48
Author(s) -
Wang Xiao,
Mou Yanhua,
Hu Jiangchun,
Wang Nan,
Zhao Li,
Liu Li,
Wang Shujin,
Meng Dali
Publication year - 2014
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201300115
Subject(s) - aspergillus versicolor , fungus , sponge , chemistry , fractionation , polyphenol , aspergillus , stereochemistry , microbiology and biotechnology , biochemistry , botany , biology , organic chemistry , antioxidant
A new dibenzo[1,4]dioxin 1 , and two new prenylated diphenyl ethers, 2 and 3 , together with six known compounds, 4 – 9 , were isolated from a sponge‐associated fungus Aspergillus versicolor Hmp‐F48 by bioactivity‐guided fractionation. Their structures were elucidated by 1D‐ and 2D‐NMR, and MS analyses. The compounds showed potent cell growth inhibitory activities against HL‐60 cell line.