Unusual Secondary Metabolites from Astragalus halicacabus Lam .

From the whole plant of Astragalus halicacabus (Sect. Halicacabus), a new cycloartane‐type glycoside, (20 R ,24 S )‐3‐ O ‐[ α ‐ L ‐arabinopyranosyl‐(1→2)‐ β ‐ D ‐xylopyranosyl]‐20,24‐epoxy‐16‐ O ‐ β ‐ D ‐glucopyranosyl‐3 β ,6 α ,16 β ,25‐tetrahydroxycycloartane, and a new glycoside, 3‐ O ‐[ β ‐ D ‐apiofuranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl]maltol were isolated together with seven known cycloartane‐type glycosides, i.e. , cyclocanthoside D, askendosides D, F, and G, cyclosieversioside G, cyclostipuloside A, elongatoside, and a known maltol glucoside, 3‐ O ‐ β ‐ D ‐glucopyranosylmaltol. The structures were elucidated by means of high‐resolution mass spectrometry, and extensive 1D‐ and 2D‐NMR spectroscopic analysis. This is the first phytochemical work on A. halicacabus , and a maltol glycoside was encountered for the first time in the Leguminosae family.