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Triterpenoids from the Stem Bark of Melia toosendan and Determination of Their Absolute Configurations at C(24)
Author(s) -
Zhang Yi,
Tang ChunPing,
Ke ChangQiang,
Yao Sheng,
Ye Yang
Publication year - 2013
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201200347
Subject(s) - triterpenoid , chemistry , absolute configuration , meliaceae , bark (sound) , stereochemistry , terpene , absolute (philosophy) , botany , biology , ecology , philosophy , epistemology
Six new triterpenoids, meliasenins S–X ( 1 – 6 , resp.), were isolated from the stem bark of Melia toosendan. Their structures were elucidated by mass spectrometry, NMR experiments, and comparison with the known compounds. Particularly, the absolute configuration at C(24) in new compounds was determined through their CD spectra of the [Pr(FOD) 3 ] complex (fod=1,1,1,2,2,3,3,7,7,7‐decafluoroheptane‐4,6‐dione) in CCl 4 , as well as by using Mosher 's method.