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Synthesis of Highly Functionalized Fluorinated Cispentacin Derivatives
Author(s) -
n Melinda,
Kiss Loránd,
Hänninen Mikko M.,
Sillanpää Reijo,
Fülöp Ferenc
Publication year - 2012
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201200323
Subject(s) - chemistry , nitrile , surface modification , bicyclic molecule , cycloaddition , 1,3 dipolar cycloaddition , oxide , combinatorial chemistry , stereochemistry , organic chemistry , catalysis
Fluorinated highly functionalized cispentacin derivatives were synthetised starting from an unsaturated bicyclic β ‐lactam through CC bond functionalization via the dipolar cycloaddition of a nitrile oxide, isoxazoline opening, and fluorination by OH/F exchange.