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Abietane Diterpenes from Hyptis suaveolens
Author(s) -
Prawatsri Saowanee,
Suksamrarn Apichart,
Chindaduang A,
Rukachaisirikul Thitima
Publication year - 2013
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201200213
Subject(s) - abietane , antimycobacterial , chemistry , traditional medicine , stereochemistry , antimicrobial , botany , diterpene , organic chemistry , biology , mycobacterium tuberculosis , medicine , tuberculosis , pathology
Investigation of the constituents of the whole plant of Hyptis suaveolens led to the isolation of three new abietane diterpenes, isosuaveolic acid ( 1 ), 8 α ,9 α ‐epoxysuaveolic acid ( 2 ), and 14‐ O ‐methylsuaveolic acid ( 3 ), together with eleven known compounds. The structures of 1 – 3 were established by spectroscopic methods and chemical correlations. Some isolates were tested for their antimycobacterial and cytotoxic activities.