Two Novel Steroidal Alkaloid Glycosides from the Seeds of  Lycium barbarum | Zendy

Wang Kun | Zendy; Sasaki Tatsunori | Zendy; Li Wei | Zendy; Li Qin | Zendy; Wang Yinghua | Zendy; Asada Yoshihisa | Zendy; Kato Hiroyoshi | Zendy; Koike Kazuo | Zendy

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Two Novel Steroidal Alkaloid Glycosides from the Seeds of Lycium barbarum

Author(s) -

Wang Kun,

Sasaki Tatsunori,

Li Wei,

Li Qin,

Wang Yinghua,

Asada Yoshihisa,

Kato Hiroyoshi,

Koike Kazuo

Publication year - 2011

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.201000293

Subject(s) - lycium , chemistry , sucrase , maltase , glycoside , alkaloid , traditional medicine , stereochemistry , biochemistry , enzyme , medicine , alternative medicine , pathology

Two novel steroidal alkaloid glycosides, lycioside A ( 1 ) and lycioside B ( 2 ) were isolated from the seeds of Lycium barbarum. Their structures were determined by various spectroscopic analyses. Compounds 1 and 2 showed inhibitory activities with the IC 50 values of 75.3 and 72.8 μ M against rat intestinal sucrase, and 63.4 and 59.1 μ M against rat intestinal maltase.

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