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Two Novel Steroidal Alkaloid Glycosides from the Seeds of Lycium barbarum
Author(s) -
Wang Kun,
Sasaki Tatsunori,
Li Wei,
Li Qin,
Wang Yinghua,
Asada Yoshihisa,
Kato Hiroyoshi,
Koike Kazuo
Publication year - 2011
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201000293
Subject(s) - lycium , chemistry , sucrase , maltase , glycoside , alkaloid , traditional medicine , stereochemistry , biochemistry , enzyme , medicine , alternative medicine , pathology
Two novel steroidal alkaloid glycosides, lycioside A ( 1 ) and lycioside B ( 2 ) were isolated from the seeds of Lycium barbarum. Their structures were determined by various spectroscopic analyses. Compounds 1 and 2 showed inhibitory activities with the IC 50 values of 75.3 and 72.8 μ M against rat intestinal sucrase, and 63.4 and 59.1 μ M against rat intestinal maltase.